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1

Biosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerol

Natsuo Ueda, Kazuhito Tsuboi, Toru Uyama, Taira Ohnishi

Journal:

Year:

2011

Language:

english

File:

PDF, 224 KB

english, 2011

2

Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D

SUN, Yong-Xin, TSUBOI, Kazuhito, OKAMOTO, Yasuo, TONAI, Takeharu, MURAKAMI, Makoto, KUDO, Ichiro, UEDA, Natsuo

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 245 KB

english, 2004

3

Inflammation of peripheral tissues and injury to peripheral nerves induce differing effects in the expression of the calcium-sensitive N-arachydonoylethanolamine-synthesizing enzyme and related molecules in rat primary sensory neurons

Sousa-Valente, João, Varga, Angelika, Torres-Perez, Jose Vicente, Jenes, Agnes, Wahba, John, Mackie, Ken, Cravatt, Benjamin, Ueda, Natsuo, Tsuboi, Kazuhito, Santha, Peter, Jancso, Gabor, Tailor, Hiren

Journal:

The Journal of Comparative Neurology

Year:

2017

Language:

english

File:

PDF, 2.40 MB

english, 2017

4

Metabolic suppression of platelet-type 12-lipoxygenase in human uterine cervix with invasive carcinoma

Santosh Nigam, G. Sravan Kumar, Mark Sutherland, Tankred Schewe, Hiroshi Ikawa, Yoshikazu Yamasaki, Natsuo Ueda, Shozo Yamamoto

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 120 KB

english, 1999

5

Biosynthetic Pathways of the Endocannabinoid Anandamide

Yasuo Okamoto, Jun Wang, Jun Morishita, Natsuo Ueda

Journal:

Chemistry & Biodiversity

Year:

2007

Language:

english

File:

PDF, 163 KB

english, 2007

6

The N-Acylethanolamine-Hydrolyzing Acid Amidase (NAAA)

Kazuhito Tsuboi, Naoko Takezaki, Natsuo Ueda

Journal:

Chemistry & Biodiversity

Year:

2007

Language:

english

File:

PDF, 177 KB

english, 2007

7

Increased 5-lipoxygenase activity in massive hepatic cell necrosis in the rat correlates with neutrophil infiltration

Norifumi Kawada, Natsuo Ueda, Dr. Yasuhiro Mizoguchi, Kenzo Kobayashi, Takeyuki Monna, Seiji Morisawa, Kazunori Ishimura, Toshiko Suzuki, Shozo Yamamoto

Journal:

Year:

1992

Language:

english

File:

PDF, 890 KB

english, 1992

8

Cyclooxygenase isozymes are expressed in human myeloma cells but not involved in anti-proliferative effect of cyclooxygenase inhibitors

Jie Ding, Kazuhito Tsuboi, Hiroshi Hoshikawa, Rieko Goto, Nozomu Mori, Michiko Katsukawa, Emi Hiraki, Shozo Yamamoto, Masahiro Abe, Natsuo Ueda

Journal:

Molecular Carcinogenesis

Year:

2006

Language:

english

File:

PDF, 262 KB

english, 2006

9

Activation of N-acylethanolamine-releasing phospholipase D by polyamines

Qian Liu, Takeharu Tonai, Natsuo Ueda

Journal:

Chemistry and Physics of Lipids

Year:

2002

Language:

english

File:

PDF, 131 KB

english, 2002

10

Possible Involvement of Interleukin-1 in Cyclooxygenase-2Induction After Spinal Cord Injury in Rats

Takeharu Tonai, Yutaka Taketani, Natsuo Ueda, Takehiko Nishisho, Yasukazu Ohmoto, Yasuyo Sakata, Masahiro Muraguchi, Kaori Wada, Shozo Yamamoto

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 266 KB

english, 1999

11

The fatty acid amide hydrolase (FAAH)

Natsuo Ueda, Robyn A Puffenbarger, Shozo Yamamoto, Dale G Deutsch

Journal:

Chemistry and Physics of Lipids

Year:

2000

Language:

english

File:

PDF, 243 KB

english, 2000

12

Synthesis of 5S-hydroxy-14, 15 LTA4 a biogenic precursor to the lipoxins

Yves Leblanc, Brian J. Fitzsimmons, Joshua Rokach, Natsuo Ueda, Shozo Yamamoto

Journal:

Tetrahedron Letters

Year:

1987

Language:

english

File:

PDF, 227 KB

english, 1987

13

Localization of Arachidonate 12-Lipoxygenase in Canine Brain Tissues

Makoto Nishiyama, Hisayo Okamoto, Takashi Watanabe, Tomokatsu Hori, Takahiko Hada, Natsuo Ueda, Shozo Yamamoto, Hideo Tsukamoto, Keiichi Watanabe, Takaaki Kirino

Journal:

Journal of Neurochemistry

Year:

1992

Language:

english

File:

PDF, 660 KB

english, 1992

14

Regional distribution and age-dependent expression of N-acylphosphatidylethanolamine-hydrolyzing phospholipase D in rat brain

Jun Morishita, Yasuo Okamoto, Kazuhito Tsuboi, Masaki Ueno, Haruhiko Sakamoto, Nobuhiro Maekawa, Natsuo Ueda

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 306 KB

english, 2005

15

Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol

Ekaterina A. Placzek, Yasuo Okamoto, Natsuo Ueda, Eric L. Barker

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 667 KB

english, 2008

16

Fatty acid cyclooxygenase induction accompanied by prostaglandin D synthesis in a human megakaryoblastic cell line CMK differentiated by phorbol ester

Shozo Yamamoto, Natsuo Ueda, Ishtiaq Mahmud, Hiroko Yamaguchi, Rieko Yamashita, Kei Yamamoto, Kazunori Ishimura, Yoshihiro Urade, Yoshihide Kanaoka, Osamu Hayaishi

Journal:

Year:

2000

Language:

english

File:

PDF, 52 KB

english, 2000

17

Lipophilic amines as potent inhibitors of N-acylethanolamine-hydrolyzing acid amidase

Yumiko Yamano, Kazuhito Tsuboi, Yuki Hozaki, Kiyohiro Takahashi, Xing-Hua Jin, Natsuo Ueda, Akimori Wada

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 670 KB

english, 2012

18

Discrimination between Two Endocannabinoids

Natsuo Ueda, Kazuhito Tsuboi

Journal:

Chemistry & Biology

Year:

2012

Language:

english

File:

PDF, 342 KB

english, 2012

19

Biology of endocannabinoid synthesis system

Jun Wang, Natsuo Ueda

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2009

Language:

english

File:

PDF, 460 KB

english, 2009

20

Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors

SravanKumar Goparaju, Natsuo Ueda, Kyoko Taniguchi, Shozo Yamamoto

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 340 KB

english, 1999

21

Ocular activity of topically administered anandamide in the rabbit

Yoichi Mikawa, Satoshi Matsuda, Tomoko Kanagawa, Tomoyuki Tajika, Natsuo Ueda, Yasuo Mimura

Journal:

Japanese Journal of Ophthalmology

Year:

1997

Language:

english

File:

PDF, 358 KB

english, 1997

22

Anandamide amidohydrolase (fatty acid amide hydrolase)

Natsuo Ueda, Shozo Yamamoto

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2000

Language:

english

File:

PDF, 242 KB

english, 2000

23

Endocannabinoid hydrolases

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2002

Language:

english

File:

PDF, 157 KB

english, 2002

24

Catalytic properties of purified recombinant anandamide amidohydrolase

Natsuo Ueda, Kazuhisa Katayama, Sravan Kumar Goparaju, Yuko Kurahashi, Kenji Yamanaka, Hiroshi Suzuki, Shozo Yamamoto

Journal:

Prostaglandins and Other Lipid Mediators

Year:

1999

Language:

english

File:

PDF, 68 KB

english, 1999

25

Cyclooxygenase-2 induction in rat spinal cord injury mediated by proinflammatory tumor necrosis factor-α and interleukin-1

Takeharu Tonai, Yutaka Taketani, Yasukazu Ohmoto, Natsuo Ueda, Takehiko Nishisho, Shozo Yamamoto

Journal:

Prostaglandins and Other Lipid Mediators

Year:

1999

Language:

english

File:

PDF, 67 KB

english, 1999

26

Different enzymes of porcine brain hydrolyzing 2-Arachidonoylglycerol, an endogenous ligand for cannabinoid receptors

Sravan Kumar Gopapaju, Natsuo Ueda, Kyoko Taniguchi, Shozo Yamamoto

Journal:

Prostaglandins and Other Lipid Mediators

Year:

1999

Language:

english

File:

PDF, 62 KB

english, 1999

27

Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells : Implications for cell proliferation and differentiation

Tiziana Bisogno, Kazuhisa Katayama, Dominique Melck, Natsuo Ueda, Luciano De Petrocellis, Shozo Yamamoto, Vincenzo Di Marzo

Journal:

Year:

1998

Language:

english

File:

PDF, 251 KB

english, 1998

28

Reversible Hydrolysis and Synthesis of Anandamide Demonstrated by Recombinant Rat Fatty-Acid Amide Hydrolase

Yuko Kurahashi, Natsuo Ueda, Hiroshi Suzuki, Mitsujiro Suzuki, Shozo Yamamoto

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 180 KB

english, 1997

29

Metabolism of Anandamide, an Endogenous Cannabinoid Receptor Ligand, in Porcine Ocular Tissues

SATOSHI MATSUDA, NOBUE KANEMITSU, AKIYO NAKAMURA, YASUO MIMURA, NATSUO UEDA, YUKO KURAHASHI, SHOZO YAMAMOTO

Journal:

Experimental Eye Research

Year:

1997

Language:

english

File:

PDF, 313 KB

english, 1997

30

Two immunologically and catalytically distinct arachidonate 12-lipoxygenases of bovine platelets and leukocytes

Yoshitaka Takahashi, Natsuo Ueda, Shozo Yamamoto

Journal:

Archives of Biochemistry and Biophysics

Year:

1988

Language:

english

File:

PDF, 854 KB

english, 1988

31

Enzyme immunoassay of thromboxane B2

Yoko Hayashi, Natsuo Ueda, Kazushige Yokota, Sumio Kawamura, Fumitaka Ogushi, Yoshiko Yamamoto, Shozo Yamamoto, Kanzen Nakamura, Kouwa Yamashita, Hiroshi Miyazaki, Kaneyoshi Kato, Shinji Terao

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1983

Language:

english

File:

PDF, 771 KB

english, 1983

32

Arachidonate 5-lipoxygenase of porcine pancreas: its localization in acinar cells

Kiyoshi Natsui, Natsuo Ueda, Shozo Yamamoto, Noriyuki Komatsu, Keiichi Watanabe

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1991

Language:

english

File:

PDF, 361 KB

english, 1991

33

Catalytic properties of human platelet 12-lipoxygenase as compared with the enzymes of other origins

Takahiko Hada, Natsuo Ueda, Yoshitaka Takahashi, Shozo Yamamoto

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1991

Language:

english

File:

PDF, 421 KB

english, 1991

34

Lipoxygenase-catalyzed oxygenation of arachidonylethanolamide, a cannabinoid receptor agonist

Natsuo Ueda, Kei Yamamoto, Shozo Yamamoto, Takashi Tokunaga, Eiji Shirakawa, Hisashi Shinkai, Masako Ogawa, Taku Sato, Ichiro Kudo, Keizo Inoue, Hiromasa Takizawa, Tatsuo Nagano, Masaaki Hirobe, Norio

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1995

Language:

english

File:

PDF, 757 KB

english, 1995

35

Lipoxin synthesis by arachidonate 12-lipoxygenase purified from porcine leukocytes

Natsuo Ueda, Chieko Yokoyama, Shozo Yamamoto, Brian J. Fitzsimmons, Joshua Rokach, John A. Oates, Alan R. Brash

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 427 KB

english, 1987

36

Immunoaffinity purification and cDNA cloning of human platelet prostaglandin endoperoxide synthase (cyclooxygenase)

Yoshitaka Takahashi, Natsuo Ueda, Tanihiro Yoshimoto, Shozo Yamamoto, Chieko Yokoyama, Atsuro Miyata, Tadashi Tanabe, Ichiro Fuse, Akira Hattori, Akira Shibata

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 453 KB

english, 1992

37

A prenylflavone, artonin E, as arachidonate 5-lipoxygenase inhibitor

Gala Ramesh Reddy, Natsuo Ueda, Takahiko Hada, Arthur Commy Sackeyfio, Shozo Yamamoto, Yoshio Hano, Miwa Aida, Taro Nomura

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 431 KB

english, 1991

38

Porcine leukocyte 5- and 12-lipoxygenases are iron enzymes

Peter M.H. Kroneck, Christophe Cucurou, Volker Ullrich, Natsuo Ueda, Hiroshi Suzuki, Tanihiro Yoshimoto, Satoshi Matsuda, Shozo Yamamoto

Journal:

Year:

1991

Language:

english

File:

PDF, 320 KB

english, 1991

39

Enzymes for anandamide biosynthesis and metabolism

Natsuo Ueda, Yuko Kurahashi, Kei Yamamoto, Shozo Yamamoto, Takashi Tokunaga

Journal:

Journal of Lipid Mediators and Cell Signalling

Year:

1996

Language:

english

File:

PDF, 275 KB

english, 1996

40

Involvement of N-acylethanolamine-hydrolyzing acid amidase in the degradation of anandamide and other N-acylethanolamines in macrophages

Yong-Xin Sun, Kazuhito Tsuboi, Li-Ying Zhao, Yasuo Okamoto, Didier M. Lambert, Natsuo Ueda

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2005

Language:

english

File:

PDF, 431 KB

english, 2005

41

Predominant expression of lysosomal N-acylethanolamine-hydrolyzing acid amidase in macrophages revealed by immunochemical studies

Kazuhito Tsuboi, Li-Ying Zhao, Yasuo Okamoto, Nobukazu Araki, Masaki Ueno, Haruhiko Sakamoto, Natsuo Ueda

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2007

Language:

english

File:

PDF, 1.17 MB

english, 2007

42

Proteolytic activation and glycosylation of N-acylethanolamine-hydrolyzing acid amidase, a lysosomal enzyme involved in the endocannabinoid metabolism

Li-Ying Zhao, Kazuhito Tsuboi, Yasuo Okamoto, Shunichiro Nagahata, Natsuo Ueda

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2007

Language:

english

File:

PDF, 833 KB

english, 2007

43

Amino acid residues crucial in pH regulation and proteolytic activation of N-acylethanolamine-hydrolyzing acid amidase

Jun Wang, Li-Ying Zhao, Toru Uyama, Kazuhito Tsuboi, Takeharu Tonai, Natsuo Ueda

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2008

Language:

english

File:

PDF, 433 KB

english, 2008

44

cDNA cloning and characterization of human and mouse Ca2+-independent phosphatidylethanolamine N-acyltransferases

Xing-Hua Jin, Toru Uyama, Jun Wang, Yasuo Okamoto, Takeharu Tonai, Natsuo Ueda

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2009

Language:

english

File:

PDF, 806 KB

english, 2009

45

Characterization of the human tumor suppressors TIG3 and HRASLS2 as phospholipid-metabolizing enzymes

Toru Uyama, Xing-Hua Jin, Kazuhito Tsuboi, Takeharu Tonai, Natsuo Ueda

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2009

Language:

english

File:

PDF, 795 KB

english, 2009

46

Enzymological studies on the biosynthesis of N-acylethanolamines

Natsuo Ueda, Kazuhito Tsuboi, Toru Uyama

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 703 KB

english, 2010

47

Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways

Kazuhito Tsuboi, Yasuo Okamoto, Natsuki Ikematsu, Manami Inoue, Yoshibumi Shimizu, Toru Uyama, Jun Wang, Dale G. Deutsch, Matthew P. Burns, Nadine M. Ulloa, Akira Tokumura, Natsuo Ueda

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2011

Language:

english

File:

PDF, 1.11 MB

english, 2011

48

Studies on the anorectic effect of N-acylphosphatidylethanolamine and phosphatidylethanolamine in mice

Niels Wellner, Kazuhito Tsuboi, Andreas Nygaard Madsen, Birgitte Holst, Thi Ai Diep, Michiyasu Nakao, Akira Tokumura, Matthew P. Burns, Dale G. Deutsch, Natsuo Ueda, Harald Severin Hansen

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2011

Language:

english

File:

PDF, 433 KB

english, 2011

49

Arachidonate 12-lipoxygenases with reference to their selective inhibitors

Shozo Yamamoto, Michiko Katsukawa, Ayumi Nakano, Emi Hiraki, Kohji Nishimura, Mitsuo Jisaka, Kazushige Yokota, Natsuo Ueda

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 313 KB

english, 2005

50

A novel type of EWS–CHOP fusion gene in myxoid liposarcoma

Yoshito Matsui, Takafumi Ueda, Takahiro Kubo, Tadashi Hasegawa, Yasuhiko Tomita, Mina Okamoto, Akira Myoui, Shigeki Kakunaga, Natsuo Yasui, Hideki Yoshikawa

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 550 KB

english, 2006

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